2 beer pints better than paracetamol for pain relief - Iffie Okoronkwo, M.D.

2 beer pints better than paracetamol for pain relief: Study

Article Published by: inshorts.com

A study conducted by researchers at the University of Greenwich, UK, has claimed that two pints of beer are better at providing pain relief than the analgesic paracetamol. Researchers stated that blood alcohol content of approximately 0.08% causes an elevation of human pain threshold along with a reduction in the pain intensity ratings.

Highlights

  • Meta-analysis of 18 controlled experiments supported analgesic effects of alcohol.
  • Alcohol resulted in a small increase in pain threshold.
  • A moderate-large decrease in pain ratings was also observed.
  • Higher blood alcohol content is associated with greater analgesia.
  • Analgesic effects may contribute to alcohol dependence in those with persistent pain.

Abstract

Despite the long-standing belief in the analgesic properties of alcohol, experimental studies have produced mixed results. This meta-analysis aimed to clarify whether alcohol produces a decrease in experimentally-induced pain and to determine the magnitude of any such effect. PubMed, PsycINFO, and Embase databases were searched from inception until April 21, 2016 for controlled studies examining the effect of quantified dosages of alcohol on pain response to noxious stimulation. Eighteen studies involving 404 participants were identified providing alcohol versus no-alcohol comparisons for 13 tests of pain threshold (n = 212) and 9 tests of pain intensity ratings (n = 192). Random effects meta-analysis of standardized mean difference (SMD) provided robust support for analgesic effects of alcohol. A mean blood alcohol content (BAC) of approximately .08% (3–4 standard drinks) produced a small elevation of pain threshold (SMD [95% CI] = .35 [.17–.54], P = .002), and a moderate to large reduction in pain intensity ratings (SMD [95% CI] = .64 [.37–.91], P < .0001), or equivalently, a mean reduction of 1.25 points on a 0- to 10-point pain rating scale. Furthermore, increasing BAC resulted in increasing analgesia, with each .02% BAC increment producing an increase of SMD = .11 for pain threshold and SMD = .20 for reduced pain intensity. Some evidence of publication bias emerged, but statistical correction methods suggested minimal impact on effect size. Taken together, findings suggest that alcohol is an effective analgesic that delivers clinically-relevant reductions in ratings of pain intensity, which could explain alcohol misuse in those with persistent pain despite its potential consequences for long-term health. Further research is needed to corroborate these findings for clinical pain states.

Perspective

This meta-analysis provides robust evidence for the analgesic properties of alcohol, which could potentially contribute to alcohol misuse in pain patients. Strongest analgesia occurs for alcohol levels exceeding World Health Organization guidelines for low-risk drinking and suggests raising awareness of alternative, less harmful pain interventions to vulnerable patients may be beneficial.


ABOUT IFFIE OKORONKWO, M.D.

Iffie Okoronkwo, M.D. is a Spine and Sports Rehabilitation Medicine and Pain Management physician at Manhattan Spine and Sports Medicine (http://www.manhattanmd.com/), a private practice based in New York City with 40 years of experience providing the finest expert medical care and services to patients around the world.

Dr. Iffie is board certified in Physical Medicine and Rehabilitation and, as a physiatrist, utilizes ultrasound guided injections, fluoroscopy guided injections, PRP, regenerative medicine, and more to evaluate and treat a variety of conditions affecting muscles, joints, ligaments, and nerves.